Cargando…
Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence
The FOXO family of transcription factors is central to the regulation of organismal longevity and cellular survival. Several studies have indicated that FOXO factors lie at the center of a complex network of upstream pathways, cofactors and downstream targets (FOXO-interaction networks), which may h...
Autores principales: | Parmentier, Frédéric, Lejeune, François-Xavier, Neri, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680703/ https://www.ncbi.nlm.nih.gov/pubmed/23781200 http://dx.doi.org/10.3389/fnagi.2013.00022 |
Ejemplares similares
-
The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease
por: Farina, Francesca, et al.
Publicado: (2017) -
Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington’s disease mice synchronous to symptoms
por: Bigan, Erwan, et al.
Publicado: (2020) -
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16(INK4a) increase
por: Voisin, Jessica, et al.
Publicado: (2020) -
Are visual impairments responsible for emotion decoding deficits in alcohol-dependence?
por: D’Hondt, Fabien, et al.
Publicado: (2014) -
A frequency-dependent decoding mechanism for axonal length sensing
por: Bressloff, Paul C., et al.
Publicado: (2015)