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Partial hepatectomy in rats results in immediate down-regulation of p27Kip1 in residual liver tissue by transcriptional and post-translational processes

Purpose: The cyclin-dependent kinase (Cdk) inhibitor p27Kip1 may be involved in regulating re-entry of residual hepatocytes into the cell cycle upon loss of liver tissue by partial hepatectomy (PH). As yet, changes in Kip1 expression during the initial period following PH are not well-characterized....

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Detalles Bibliográficos
Autores principales: Rohlfing, Anne-Katrin, Trescher, Karoline, Hähnel, Juliane, Müller, Christian, Hildebrandt, Jan-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680744/
https://www.ncbi.nlm.nih.gov/pubmed/23781207
http://dx.doi.org/10.3389/fphys.2013.00139