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Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

Safety is the foremost issue in all human cell therapies, but human induced pluripotent stem cells (iPSCs) currently lack a useful safety indicator. Studies in chimeric mice have demonstrated that certain lines of iPSCs are tumorigenic; however a similar screen has not been developed for human iPSCs...

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Detalles Bibliográficos
Autores principales: Yamashita, Akihiro, Liu, Shiying, Woltjen, Knut, Thomas, Bradley, Meng, Guoliang, Hotta, Akitsu, Takahashi, Kazutoshi, Ellis, James, Yamanaka, Shinya, Rancourt, Derrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680803/
https://www.ncbi.nlm.nih.gov/pubmed/23760219
http://dx.doi.org/10.1038/srep01978