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Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells
Safety is the foremost issue in all human cell therapies, but human induced pluripotent stem cells (iPSCs) currently lack a useful safety indicator. Studies in chimeric mice have demonstrated that certain lines of iPSCs are tumorigenic; however a similar screen has not been developed for human iPSCs...
Autores principales: | Yamashita, Akihiro, Liu, Shiying, Woltjen, Knut, Thomas, Bradley, Meng, Guoliang, Hotta, Akitsu, Takahashi, Kazutoshi, Ellis, James, Yamanaka, Shinya, Rancourt, Derrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680803/ https://www.ncbi.nlm.nih.gov/pubmed/23760219 http://dx.doi.org/10.1038/srep01978 |
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