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Investigation of NADH Binding, Hydride Transfer, and NAD(+) Dissociation during NADH Oxidation by Mitochondrial Complex I Using Modified Nicotinamide Nucleotides
[Image: see text] NADH:ubiquinone oxidoreductase (complex I) is a complicated respiratory enzyme that conserves the energy from NADH oxidation, coupled to ubiquinone reduction, as a proton motive force across the mitochondrial inner membrane. During catalysis, NADH oxidation by a flavin mononucleoti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680915/ https://www.ncbi.nlm.nih.gov/pubmed/23683271 http://dx.doi.org/10.1021/bi3016873 |