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Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions

INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models of breast carcinogenesis include LCIS as a precursor of low-grade carcinomas. We provide evidence favoring a clonal origin for LCIS and synchronous es...

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Detalles Bibliográficos
Autores principales: Andrade, Victor P, Ostrovnaya, Irina, Seshan, Venkatraman E, Morrogh, Mary, Giri, Dilip, Olvera, Narciso, De Brot, Marina, Morrow, Monica, Begg, Colin B, King, Tari A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680923/
https://www.ncbi.nlm.nih.gov/pubmed/22776144
http://dx.doi.org/10.1186/bcr3222