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Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer

INTRODUCTION: The purpose of this investigation was to evaluate the efficacy of cisplatin chemotherapy in BRCA1 mutation carriers with metastatic breast cancer. METHODS: In a phase II, open-label study, 20 patients with metastatic breast cancer who carried a mutation in BRCA1 were treated with cispl...

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Detalles Bibliográficos
Autores principales: Byrski, Tomasz, Dent, Rebecca, Blecharz, Pawel, Foszczynska-Kloda, Malgorzata, Gronwald, Jacek, Huzarski, Tomasz, Cybulski, Cezary, Marczyk, Elzbieta, Chrzan, Robert, Eisen, Andrea, Lubinski, Jan, Narod, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680929/
https://www.ncbi.nlm.nih.gov/pubmed/22817698
http://dx.doi.org/10.1186/bcr3231