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Hippo inactivation feeds tumor-initiating cells

The Hippo pathway has emerged as a well-conserved kinase cascade controlling cell proliferation and survival and has recently gained much attention for its key activity as a tumor suppressor. In a study published in Cell, Cordenonsi and colleagues link TAZ, a downstream effector of the Hippo pathway...

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Detalles Bibliográficos
Autores principales: Duss, Stephan, Britschgi, Adrian, Bentires-Alj, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680934/
https://www.ncbi.nlm.nih.gov/pubmed/22866917
http://dx.doi.org/10.1186/bcr3190