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Diagnostic criteria, specific mutations, and genetic predisposition in gastrointestinal stromal tumors
In 1998, gastrointestinal stromal tumor (GIST) emerged as a distinct oncogenetic entity and subsequently became a paradigm of targeted therapies in solid tumors. Diagnosis of GIST relies on both histology and immunohistochemistry. Ninety-five percent of GISTs express either KIT or DOG-1. Approximate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681166/ https://www.ncbi.nlm.nih.gov/pubmed/23776354 http://dx.doi.org/10.2147/TACG.S7191 |