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FAM13A locus in COPD is independently associated with lung cancer – evidence of a molecular genetic link between COPD and lung cancer

Recent genome-wide association studies have reported a FAM13A variant on chromosome 4q22.1 is associated with lung function and COPD. We examined this variant in a case-control study of current or former smokers with chronic obstructive pulmonary disease (COPD, n = 458), lung cancer (n = 454), or no...

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Detalles Bibliográficos
Autores principales: Young, Robert P, Hopkins, Raewyn J, Hay, Bryan A, Whittington, Chris F, Epton, Michael J, Gamble, Gregory D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681173/
https://www.ncbi.nlm.nih.gov/pubmed/23776362
http://dx.doi.org/10.2147/TACG.S15758