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Mineral and Matrix Changes in Brtl/+ Teeth Provide Insights into Mineralization Mechanisms

The Brtl/+ mouse is a knock-in model for osteogenesis imperfecta type IV in which a Gly349Cys substitution was introduced into one COL1A1 allele. To gain insight into the changes in dentin structure and mineral composition in these transgenic mice, the objective of this study was to use microcompute...

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Detalles Bibliográficos
Autores principales: Boskey, Adele L., Verdelis, Kostas, Spevak, Lyudmila, Lukashova, Lyudmila, Beniash, Elia, Yang, Xu, Cabral, Wayne A., Marini, Joan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681234/
https://www.ncbi.nlm.nih.gov/pubmed/23802117
http://dx.doi.org/10.1155/2013/295812