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Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

Relapsed childhood acute lymphoblastic leukemia (ALL) carries a poor prognosis despite intensive retreatment, due to intrinsic drug resistance(1-2). The biological pathways that mediate resistance are unknown. Here we report the transcriptome profiles of matched diagnosis and relapse bone marrow spe...

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Detalles Bibliográficos
Autores principales: Meyer, Julia A., Wang, Jinhua, Hogan, Laura E., Yang, Jun J., Dandekar, Smita, Patel, Jay P., Tang, Zuojian, Zumbo, Paul, Li, Sheng, Zavadil, Jiri, Levine, Ross L., Cardozo, Timothy, Hunger, Stephen P., Raetz, Elizabeth A., Evans, William E., Morrison, Debra J., Mason, Christopher E., Carroll, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681285/
https://www.ncbi.nlm.nih.gov/pubmed/23377183
http://dx.doi.org/10.1038/ng.2558