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Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
Relapsed childhood acute lymphoblastic leukemia (ALL) carries a poor prognosis despite intensive retreatment, due to intrinsic drug resistance(1-2). The biological pathways that mediate resistance are unknown. Here we report the transcriptome profiles of matched diagnosis and relapse bone marrow spe...
Autores principales: | Meyer, Julia A., Wang, Jinhua, Hogan, Laura E., Yang, Jun J., Dandekar, Smita, Patel, Jay P., Tang, Zuojian, Zumbo, Paul, Li, Sheng, Zavadil, Jiri, Levine, Ross L., Cardozo, Timothy, Hunger, Stephen P., Raetz, Elizabeth A., Evans, William E., Morrison, Debra J., Mason, Christopher E., Carroll, William L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681285/ https://www.ncbi.nlm.nih.gov/pubmed/23377183 http://dx.doi.org/10.1038/ng.2558 |
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