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Fenofibrate administration to arthritic rats increases adiponectin and leptin and prevents oxidative muscle wasting

Chronic inflammation induces skeletal muscle wasting and cachexia. In arthritic rats, fenofibrate, a peroxisome proliferator-activated receptor α (PPARα (PPARA)) agonist, reduces wasting of gastrocnemius, a predominantly glycolytic muscle, by decreasing atrogenes and myostatin. Considering that feno...

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Detalles Bibliográficos
Autores principales:	Castillero, Estíbaliz, Martín, Ana Isabel, Nieto-Bona, Maria Paz, Fernández-Galaz, Carmen, López-Menduiña, María, Villanúa, María Ángeles, López-Calderón, Asunción
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681315/ https://www.ncbi.nlm.nih.gov/pubmed/23781298 http://dx.doi.org/10.1530/EC-12-0003

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