Cargando…
Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer
BACKGROUND: Insulin-like growth factor 2 (IGF2) is the predominant IGF in adults and regulates cell growth. In contrast to normal tissues, where IGF2 is imprinted and only expressed from the paternal allele, loss of imprinting (LOI) and biallelic IGF2 expression are observed in many cancers includin...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681323/ https://www.ncbi.nlm.nih.gov/pubmed/23781309 http://dx.doi.org/10.1530/EC-12-0054 |