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Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer

BACKGROUND: Insulin-like growth factor 2 (IGF2) is the predominant IGF in adults and regulates cell growth. In contrast to normal tissues, where IGF2 is imprinted and only expressed from the paternal allele, loss of imprinting (LOI) and biallelic IGF2 expression are observed in many cancers includin...

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Detalles Bibliográficos
Autores principales:	Belharazem, Djeda, Kirchner, Matthias, Geissler, Franziska, Bugert, Peter, Spahn, Martin, Kneitz, Burkhard, Riedmiller, Hubertus, Sauer, Christian, Küffer, Stefan, Trojan, Lutz, Bolenz, Christian, Michel, Maurice Stephan, Marx, Alexander, Ströbel, Philipp
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681323/ https://www.ncbi.nlm.nih.gov/pubmed/23781309 http://dx.doi.org/10.1530/EC-12-0054

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