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Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis

INTRODUCTION: Cannabinoid receptor 2 (CB2R) expression is upregulated during sepsis. However, there are conflicting results regarding the effects of CB2R modulation in the hyperinflammatory phase of the disease. The aim of this study was therefore to investigate the effects of CB2R manipulation on l...

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Detalles Bibliográficos
Autores principales: Lehmann, Christian, Kianian, Mandana, Zhou, Juan, Küster, Inga, Kuschnereit, Rieke, Whynot, Sara, Hung, Orlando, Shukla, Romesh, Johnston, Brent, Cerny, Vladimir, Pavlovic, Dragan, Spassov, Alexander, Kelly, Melanie EM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681373/
https://www.ncbi.nlm.nih.gov/pubmed/22420504
http://dx.doi.org/10.1186/cc11248