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PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes

PIK3CA mutations are frequently diagnosed in diverse cancers and may predict response to PI3K/AKT/mTOR inhibitors. It remains unclear whether they are associated with other characteristics. We analyzed characteristics and outcome of 90 consecutive patients with diverse advanced tumors and PIK3CA mut...

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Detalles Bibliográficos
Autores principales: Janku, Filip, Wheler, Jennifer J., Naing, Aung, Stepanek, Vanda M., Falchook, Gerald S., Fu, Siqing, Garrido-Laguna, Ignacio, Tsimberidou, Apostolia M., Piha-Paul, Sarina A., Moulder, Stacy L., Lee, J. Jack, Luthra, Rajyalakshmi, Hong, David S., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681495/
https://www.ncbi.nlm.nih.gov/pubmed/23248156