STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia

We recently reported that chronic myeloid leukaemia (CML) patients harbour high levels of STAT5 when they progress to advanced phases of disease. Advanced disease is characterized by an increased incidence of BCR-ABL1 mutations. We now describe a highly significant correlation between STAT5 expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Gille, Lars, Cerny-Reiterer, Sabine, Tigan, Anca-Sarmiza, Hoelbl-Kovacic, Andrea, Valent, Peter, Moriggl, Richard, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681503/
https://www.ncbi.nlm.nih.gov/pubmed/23458731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681503/
https://www.ncbi.nlm.nih.gov/pubmed/23458731

Ejemplares similares