A Spontaneous, Recurrent Mutation in Divalent Metal Transporter-1 Exposes a Calcium Entry Pathway

Divalent metal transporter-1 (DMT1/DCT1/Nramp2) is the major Fe(2+) transporter mediating cellular iron uptake in mammals. Phenotypic analyses of animals with spontaneous mutations in DMT1 indicate that it functions at two distinct sites, transporting dietary iron across the apical membrane of intes...

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Detalles Bibliográficos
Autores principales: Xu, Haoxing, Jin, Jie, DeFelice, Louis J, Andrews, Nancy C, Clapham, David E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368157/
https://www.ncbi.nlm.nih.gov/pubmed/15024413
http://dx.doi.org/10.1371/journal.pbio.0020050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368157/
https://www.ncbi.nlm.nih.gov/pubmed/15024413
http://dx.doi.org/10.1371/journal.pbio.0020050

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