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Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence

Reactive oxygen species (ROS) can induce premature cellular senescence, which is believed to contribute to aging and age-related diseases. The nuclear erythroid 2 p45–related factor-2 (Nrf2) is a transcription factor that mediates cytoprotective responses against stress. We demonstrate that caveolin...

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Detalles Bibliográficos
Autores principales: Volonte, Daniela, Liu, Zhongmin, Musille, Paul M., Stoppani, Elena, Wakabayashi, Nobunao, Di, Yuan-Pu, Lisanti, Michael P., Kensler, Thomas W., Galbiati, Ferruccio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681691/
https://www.ncbi.nlm.nih.gov/pubmed/23637463
http://dx.doi.org/10.1091/mbc.E12-09-0666