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Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
Reactive oxygen species (ROS) can induce premature cellular senescence, which is believed to contribute to aging and age-related diseases. The nuclear erythroid 2 p45–related factor-2 (Nrf2) is a transcription factor that mediates cytoprotective responses against stress. We demonstrate that caveolin...
Autores principales: | Volonte, Daniela, Liu, Zhongmin, Musille, Paul M., Stoppani, Elena, Wakabayashi, Nobunao, Di, Yuan-Pu, Lisanti, Michael P., Kensler, Thomas W., Galbiati, Ferruccio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681691/ https://www.ncbi.nlm.nih.gov/pubmed/23637463 http://dx.doi.org/10.1091/mbc.E12-09-0666 |
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