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Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration

The Rho family of GTPases plays an important role in coordinating dynamic changes in the cell migration machinery after integrin engagement with the extracellular matrix. Rho GTPases are activated by guanine nucleotide exchange factors (GEFs) and negatively regulated by GTPase-activating proteins (G...

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Detalles Bibliográficos
Autores principales: Jones, Matthew C., Machida, Kazuya, Mayer, Bruce J., Turner, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681694/
https://www.ncbi.nlm.nih.gov/pubmed/23615439
http://dx.doi.org/10.1091/mbc.E12-09-0654