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Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration
The Rho family of GTPases plays an important role in coordinating dynamic changes in the cell migration machinery after integrin engagement with the extracellular matrix. Rho GTPases are activated by guanine nucleotide exchange factors (GEFs) and negatively regulated by GTPase-activating proteins (G...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681694/ https://www.ncbi.nlm.nih.gov/pubmed/23615439 http://dx.doi.org/10.1091/mbc.E12-09-0654 |