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Nebulin binding impedes mutant desmin filament assembly

Desmin intermediate filaments (DIFs) form an intricate meshwork that organizes myofibers within striated muscle cells. The mechanisms that regulate the association of desmin to sarcomeres and their role in desminopathy are incompletely understood. Here we compare the effect nebulin binding has on th...

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Detalles Bibliográficos
Autores principales: Baker, Laura K., Gillis, David C., Sharma, Sarika, Ambrus, Andy, Herrmann, Harald, Conover, Gloria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681697/
https://www.ncbi.nlm.nih.gov/pubmed/23615443
http://dx.doi.org/10.1091/mbc.E12-11-0840