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Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization

The sorting signals that direct proteins to the apical surface of polarized epithelial cells are complex and can include posttranslational modifications, such as N- and O-linked glycosylation. Efficient apical sorting of the neurotrophin receptor p75 is dependent on its O-glycosylated membrane proxi...

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Detalles Bibliográficos
Autores principales: Youker, Robert T., Bruns, Jennifer R., Costa, Simone A., Rbaibi, Youssef, Lanni, Frederick, Kashlan, Ossama B., Teng, Haibing, Weisz, Ora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681702/
https://www.ncbi.nlm.nih.gov/pubmed/23637462
http://dx.doi.org/10.1091/mbc.E13-02-0078