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Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae
The centromeric histone H3 variant (CenH3) is essential for chromosome segregation in eukaryotes. We identify posttranslational modifications of Saccharomyces cerevisiae CenH3, Cse4. Functional characterization of cse4 phosphorylation mutants shows growth and chromosome segregation defects when comb...
Autores principales: | Boeckmann, Lars, Takahashi, Yoshimitsu, Au, Wei-Chun, Mishra, Prashant K., Choy, John S., Dawson, Anthony R., Szeto, May Y., Waybright, Timothy J., Heger, Christopher, McAndrew, Christopher, Goldsmith, Paul K., Veenstra, Timothy D., Baker, Richard E., Basrai, Munira A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681705/ https://www.ncbi.nlm.nih.gov/pubmed/23637466 http://dx.doi.org/10.1091/mbc.E12-12-0893 |
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