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Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae

The centromeric histone H3 variant (CenH3) is essential for chromosome segregation in eukaryotes. We identify posttranslational modifications of Saccharomyces cerevisiae CenH3, Cse4. Functional characterization of cse4 phosphorylation mutants shows growth and chromosome segregation defects when comb...

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Detalles Bibliográficos
Autores principales: Boeckmann, Lars, Takahashi, Yoshimitsu, Au, Wei-Chun, Mishra, Prashant K., Choy, John S., Dawson, Anthony R., Szeto, May Y., Waybright, Timothy J., Heger, Christopher, McAndrew, Christopher, Goldsmith, Paul K., Veenstra, Timothy D., Baker, Richard E., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681705/
https://www.ncbi.nlm.nih.gov/pubmed/23637466
http://dx.doi.org/10.1091/mbc.E12-12-0893