Cargando…

JNK1/2 regulates ER–mitochondrial Ca(2+) cross-talk during IL-1β–mediated cell death in RINm5F and human primary β-cells

Elevated interleukin-1β (IL-1β) induces apoptosis in pancreatic β-cells through endoplasmic reticulum (ER) stress induction and subsequent c-jun-N-terminal kinase 1/2 (JNK1/2) activation. In earlier work we showed that JNK1/2 activation is initiated before ER stress and apoptotic induction in respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verma, Gaurav, Bhatia, Himanshi, Datta, Malabika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681707/ https://www.ncbi.nlm.nih.gov/pubmed/23615449 http://dx.doi.org/10.1091/mbc.E12-12-0885

Ejemplares similares

Functional Ryanodine Receptors in the Plasma Membrane of RINm5F Pancreatic β-Cells
por: Rosker, Christian, et al.
Publicado: (2009)

Tat-CIAPIN1 protein prevents against cytokine-induced cytotoxicity in pancreatic RINm5F β-cells
por: Yeo, Hyeon Ji, et al.
Publicado: (2021)

Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model
por: Yeo, Hyeon Ji, et al.
Publicado: (2023)

Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis
por: Liu, Xi, et al.
Publicado: (2020)

Role of Calmodulin-Calmodulin Kinase II, cAMP/Protein Kinase A and ERK 1/2 on Aeromonas hydrophila-Induced Apoptosis of Head Kidney Macrophages
por: Banerjee, Chaitali, et al.
Publicado: (2014)

Amyloid β Oligomers Increase ER-Mitochondria Ca(2+) Cross Talk in Young Hippocampal Neurons and Exacerbate Aging-Induced Intracellular Ca(2+) Remodeling
por: Calvo-Rodriguez, Maria, et al.
Publicado: (2019)

Leptin induces inflammation-related genes in RINm5F insulinoma cells
por: Hekerman, Paul, et al.
Publicado: (2007)

NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection
por: Pu, Ze‐qing, et al.
Publicado: (2020)

AQP8 is a crucial H(2)O(2) transporter in insulin-producing RINm5F cells
por: Krüger, Christina, et al.
Publicado: (2021)

Transduced Tat-DJ-1 protein inhibits cytokines-induced pancreatic RINm5F cell death
por: Jo, Hyo Sang, et al.
Publicado: (2016)

Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio
por: Yi, Jingwen, et al.
Publicado: (2015)

Streptozotocin and Alloxan-based Selection Improves Toxin Resistance of Insulin-Producing RINm Cells
por: Bloch, Konstantin O., et al.
Publicado: (2000)

Effect of glucose on the expression of c-myc gene in cultured RINm5F cell.
por: Kim, S. W., et al.
Publicado: (1991)

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia
por: Rago, Vittoria, et al.
Publicado: (2009)

Cross talk between β subunits, intracellular Ca(2+) signaling, and SNAREs in the modulation of Ca(V)2.1 channel steady‐state inactivation
por: Serra, Selma Angèlica, et al.
Publicado: (2018)

The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling
por: Faria, Michelle, et al.
Publicado: (2018)

Both JNK1 and JNK2 Are Indispensable for Sensitized Extracellular Matrix Mineralization in IKKβ-Deficient Osteoblasts
por: Hao, Qianyun, et al.
Publicado: (2020)

Cross-talk between TGF-β1 and IL-6 in human trabecular meshwork cells
por: Liton, Paloma B., et al.
Publicado: (2009)

JNK2 is activated during ER stress and promotes cell survival
por: Raciti, M, et al.
Publicado: (2012)

Folate Deficiency Triggers an Oxidative-Nitrosative Stress-Mediated Apoptotic Cell Death and Impedes Insulin Biosynthesis in RINm5F Pancreatic Islet β–Cells: Relevant to the Pathogenesis of Diabetes
por: Hsu, Hung-Chih, et al.
Publicado: (2013)

Oxidative Stress Type Influences the Properties of Antioxidants Containing Polyphenols in RINm5F Beta Cells
por: Auberval, Nathalie, et al.
Publicado: (2015)

GSK3β Is Involved in JNK2-Mediated β-Catenin Inhibition
por: Hu, Dong, et al.
Publicado: (2009)

ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid
por: Meligova, Aggeliki K., et al.
Publicado: (2023)

NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving
por: Pu, Ze-qing, et al.
Publicado: (2021)

Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA(2)β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes
por: Ali, Tomader, et al.
Publicado: (2021)

Beneficial Effect of Jojoba Seed Extracts on Hyperglycemia-Induced Oxidative Stress in RINm5f Beta Cells
por: Belhadj, Sahla, et al.
Publicado: (2018)

The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells
por: Helbig, Christiane, et al.
Publicado: (2020)

AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress
por: Rasool, R U, et al.
Publicado: (2017)

Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells
por: Hwang, In-Hu, et al.
Publicado: (2016)

GRP75 mediates endoplasmic reticulum–mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis
por: Tiwary, Shweta, et al.
Publicado: (2021)

β cell ER stress and the implications for immunogenicity in type 1 diabetes
por: Marré, Meghan L., et al.
Publicado: (2015)

Metabolic regulation of the K(ATP) and a maxi-K(V) channel in the insulin-secreting RINm5F cell
Publicado: (1988)

The Anemonia sulcata Toxin BDS-I Protects Astrocytes Exposed to Aβ(1–42) Oligomers by Restoring [Ca(2+)](i) Transients and ER Ca(2+) Signaling
por: Piccialli, Ilaria, et al.
Publicado: (2020)

Ficolin-2 amplifies inflammation in macrophage-smooth muscle cell cross-talk and increases monocyte transmigration by mechanisms involving IL-1β and IL-6
por: Macarie, Răzvan Daniel, et al.
Publicado: (2023)

Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation
por: Jo, Hyo Sang, et al.
Publicado: (2016)

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells
por: Dickerson, Matthew T., et al.
Publicado: (2017)

IL-1β Promotes TGF-β1 and IL-2 Dependent Foxp3 Expression in Regulatory T Cells
por: Ganesh, Balaji B., et al.
Publicado: (2011)

JNK activation is essential for activation of MEK/ERK signaling in IL-1β-induced COX-2 expression in synovial fibroblasts
por: Kitanaka, Taku, et al.
Publicado: (2017)

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells
por: Pinton, Giulia, et al.
Publicado: (2016)

The Impact of the Ca(2+)-Independent Phospholipase A(2)β (iPLA(2)β) on Immune Cells
por: White, Tayleur D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rdseiikk4drvea4iofsas17h3u