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N-Terminal Phosphorylation of the Dopamine Transporter Is Required for Amphetamine-Induced Efflux

Amphetamine (AMPH) elicits its behavioral effects by acting on the dopamine (DA) transporter (DAT) to induce DA efflux into the synaptic cleft. We previously demonstrated that a human DAT construct in which the first 22 amino acids were truncated was not phosphorylated by activation of protein kinas...

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Detalles Bibliográficos
Autores principales: Khoshbouei, Habibeh, Sen, Namita, Guptaroy, Bipasha, Johnson, L'Aurelle, Lund, David, Gnegy, Margaret E, Galli, Aurelio, Javitch, Jonathan A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368172/
https://www.ncbi.nlm.nih.gov/pubmed/15024426
http://dx.doi.org/10.1371/journal.pbio.0020078