Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage

BACKGROUND: Cidofovir (CDV) proved efficacious in treatment of human papillomaviruses (HPVs) hyperplasias. Antiproliferative effects of CDV have been associated with apoptosis induction, S-phase accumulation, and increased levels of tumor suppressor proteins. However, the molecular mechanisms for th...

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Detalles Bibliográficos
Autores principales: De Schutter, Tim, Andrei, Graciela, Topalis, Dimitri, Naesens, Lieve, Snoeck, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681722/
https://www.ncbi.nlm.nih.gov/pubmed/23702334
http://dx.doi.org/10.1186/1755-8794-6-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681722/
https://www.ncbi.nlm.nih.gov/pubmed/23702334
http://dx.doi.org/10.1186/1755-8794-6-18

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