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Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage
BACKGROUND: Cidofovir (CDV) proved efficacious in treatment of human papillomaviruses (HPVs) hyperplasias. Antiproliferative effects of CDV have been associated with apoptosis induction, S-phase accumulation, and increased levels of tumor suppressor proteins. However, the molecular mechanisms for th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681722/ https://www.ncbi.nlm.nih.gov/pubmed/23702334 http://dx.doi.org/10.1186/1755-8794-6-18 |