Host Defense and Recruitment of Foxp3(+) T Regulatory Cells to the Lungs in Chronic Mycobacterium tuberculosis Infection Requires Toll-like Receptor 2

Acute resistance to low dose M. tuberculosis (Mtb) infection is not dependent on Toll-like receptor (TLR) 2. However, whether TLR2 contributes to resistance in chronic Mtb infection has remained uncertain. Here we report that, following low dose aerosol infection with Mtb, mice lacking TLR2 (TLR2KO)...

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Detalles Bibliográficos
Autores principales: McBride, Amanda, Konowich, Jill, Salgame, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681744/
https://www.ncbi.nlm.nih.gov/pubmed/23785280
http://dx.doi.org/10.1371/journal.ppat.1003397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681744/
https://www.ncbi.nlm.nih.gov/pubmed/23785280
http://dx.doi.org/10.1371/journal.ppat.1003397

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