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Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development

Glycan masking is an emerging vaccine design strategy to focus antibody responses to specific epitopes, but it has mostly been evaluated on the already heavily glycosylated HIV gp120 envelope glycoprotein. Here this approach was used to investigate the binding interaction of Plasmodium vivax Duffy B...

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Detalles Bibliográficos
Autores principales: Sampath, Sowmya, Carrico, Chris, Janes, Joel, Gurumoorthy, Sairam, Gibson, Claire, Melcher, Martin, Chitnis, Chetan E., Wang, Ruobing, Schief, William R., Smith, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681752/
https://www.ncbi.nlm.nih.gov/pubmed/23853575
http://dx.doi.org/10.1371/journal.ppat.1003420