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Isogarcinol Is a New Immunosuppressant

Calcineurin (CN), a unique protein phosphatase, plays an important role in immune regulation. In this study we used CN as a target enzyme to investigate the immunosuppressive properties of a series of natural compounds from Garcinia mangostana L., and discovered an active compound, isogarcinol. Enzy...

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Detalles Bibliográficos
Autores principales: Cen, Juren, Shi, Mingshu, Yang, Yanfang, Fu, Yanxia, Zhou, Hailing, Wang, Mengqi, Su, Zhenyi, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681756/
https://www.ncbi.nlm.nih.gov/pubmed/23785505
http://dx.doi.org/10.1371/journal.pone.0066503