Combinatorial Library of Improved Peptide Aptamers, CLIPs to Inhibit RAGE Signal Transduction in Mammalian Cells

Peptide aptamers are small proteins containing a randomized peptide sequence embedded into a stable protein scaffold, such as Thioredoxin. We developed a robust method for building a Combinatorial Library of Improved Peptide aptamers (CLIPs) of high complexity, containing ≥3×10(10) independent clone...

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Detalles Bibliográficos
Autores principales: Reverdatto, Sergey, Rai, Vivek, Xue, Jing, Burz, David S., Schmidt, Ann Marie, Shekhtman, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681763/
https://www.ncbi.nlm.nih.gov/pubmed/23785412
http://dx.doi.org/10.1371/journal.pone.0065180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681763/
https://www.ncbi.nlm.nih.gov/pubmed/23785412
http://dx.doi.org/10.1371/journal.pone.0065180

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