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Hepatic Adaptation Compensates Inactivation of Intestinal Arginine Biosynthesis in Suckling Mice

Suckling mammals, including mice, differ from adults in the abundant expression of enzymes that synthesize arginine from citrulline in their enterocytes. To investigate the importance of the small-intestinal arginine synthesis for whole-body arginine production in suckling mice, we floxed exon 13 of...

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Detalles Bibliográficos
Autores principales: Marion, Vincent, Sankaranarayanan, Selvakumari, de Theije, Chiel, van Dijk, Paul, Hakvoort, Theo B. M., Lamers, Wouter H., Köhler, Eleonore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681768/
https://www.ncbi.nlm.nih.gov/pubmed/23785515
http://dx.doi.org/10.1371/journal.pone.0067021