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Hepatic Adaptation Compensates Inactivation of Intestinal Arginine Biosynthesis in Suckling Mice
Suckling mammals, including mice, differ from adults in the abundant expression of enzymes that synthesize arginine from citrulline in their enterocytes. To investigate the importance of the small-intestinal arginine synthesis for whole-body arginine production in suckling mice, we floxed exon 13 of...
Autores principales: | Marion, Vincent, Sankaranarayanan, Selvakumari, de Theije, Chiel, van Dijk, Paul, Hakvoort, Theo B. M., Lamers, Wouter H., Köhler, Eleonore S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681768/ https://www.ncbi.nlm.nih.gov/pubmed/23785515 http://dx.doi.org/10.1371/journal.pone.0067021 |
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