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Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma

Glucocorticoid-induced TNF receptor (GITR) plays a crucial role in modulating immune response and inflammation, however the role of GITR in human cancers is poorly understood. In this study, we demonstrated that GITR is inactivated during tumor progression in Multiple Myeloma (MM) through promoter C...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Quang, Phong, Braggio, Esteban, Ngo, Hai, Badalian-Very, Gayane, Flores, Ludmila, Zhang, Yong, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Azab, Feda, Carrasco, Ruben, Rollins, Barrett J., Roccaro, Aldo M., Ghobrial, Irene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681775/
https://www.ncbi.nlm.nih.gov/pubmed/23785514
http://dx.doi.org/10.1371/journal.pone.0066982