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Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma
Glucocorticoid-induced TNF receptor (GITR) plays a crucial role in modulating immune response and inflammation, however the role of GITR in human cancers is poorly understood. In this study, we demonstrated that GITR is inactivated during tumor progression in Multiple Myeloma (MM) through promoter C...
Autores principales: | Liu, Yang, Quang, Phong, Braggio, Esteban, Ngo, Hai, Badalian-Very, Gayane, Flores, Ludmila, Zhang, Yong, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Azab, Feda, Carrasco, Ruben, Rollins, Barrett J., Roccaro, Aldo M., Ghobrial, Irene M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681775/ https://www.ncbi.nlm.nih.gov/pubmed/23785514 http://dx.doi.org/10.1371/journal.pone.0066982 |
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