A Loss-of-Function Screen for Phosphatases that Regulate Neurite Outgrowth Identifies PTPN12 as a Negative Regulator of TrkB Tyrosine Phosphorylation

Alterations in function of the neurotrophin BDNF are associated with neurodegeneration, cognitive decline, and psychiatric disorders. BDNF promotes axonal outgrowth and branching, regulates dendritic tree morphology and is important for axonal regeneration after injury, responses that largely result...

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Detalles Bibliográficos
Autores principales: Ambjørn, Malene, Dubreuil, Véronique, Miozzo, Federico, Nigon, Fabienne, Møller, Bente, Issazadeh-Navikas, Shohreh, Berg, Jacob, Lees, Michael, Sap, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681791/
https://www.ncbi.nlm.nih.gov/pubmed/23785422
http://dx.doi.org/10.1371/journal.pone.0065371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681791/
https://www.ncbi.nlm.nih.gov/pubmed/23785422
http://dx.doi.org/10.1371/journal.pone.0065371

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