Hypomethylation of Serum Blood Clot DNA, but Not Plasma EDTA-Blood Cell Pellet DNA, from Vitamin B12-Deficient Subjects

Vitamin B12, a co-factor in methyl-group transfer, is important in maintaining DNA (deoxycytidine) methylation. Using two independent assays we examined the effect of vitamin B12-deficiency (plasma vitamin B12<148 pmol/L) on DNA methylation in women of childbearing age. Coagulated blood clot DNA...

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Detalles Bibliográficos
Autores principales: Quinlivan, Eoin P., Crider, Krista S., Zhu, Jiang-Hui, Maneval, David R., Hao, Ling, Li, Zhu, Rasmussen, Sonja A., Berry, R. J., Bailey, Lynn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681792/
https://www.ncbi.nlm.nih.gov/pubmed/23785415
http://dx.doi.org/10.1371/journal.pone.0065241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681792/
https://www.ncbi.nlm.nih.gov/pubmed/23785415
http://dx.doi.org/10.1371/journal.pone.0065241

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