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Hypoxia–Induced Cytotoxic Drug Resistance in Osteosarcoma Is Independent of HIF-1Alpha

Survival rates from childhood cancer have improved dramatically in the last 40 years, such that over 80% of children are now cured. However in certain subgroups, including metastatic osteosarcoma, survival has remained stubbornly poor, despite dose intensive multi-agent chemotherapy regimens, and ne...

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Detalles Bibliográficos
Autores principales: Adamski, Jennifer, Price, Andrew, Dive, Caroline, Makin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681794/
https://www.ncbi.nlm.nih.gov/pubmed/23785417
http://dx.doi.org/10.1371/journal.pone.0065304