The Adjuvant Activity of Alphavirus Replicons Is Enhanced by Incorporating the Microbial Molecule Flagellin into the Replicon

Ligands of pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) stimulate innate and adaptive immune responses and are considered as potent adjuvants. Combinations of ligands might act in synergy to induce stronger and broader immune responses compared to stand-alone ligands. Al...

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Detalles Bibliográficos
Autores principales: Knudsen, Maria L., Johansson, Daniel X., Kostic, Linda, Nordström, Eva K. L., Tegerstedt, Karin, Pasetto, Anna, Applequist, Steven E., Ljungberg, Karl, Sirard, Jean-Claude, Liljeström, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681802/
https://www.ncbi.nlm.nih.gov/pubmed/23785460
http://dx.doi.org/10.1371/journal.pone.0065964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681802/
https://www.ncbi.nlm.nih.gov/pubmed/23785460
http://dx.doi.org/10.1371/journal.pone.0065964

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