Prospect of Bioflavonoid Fisetin as a Quadruplex DNA Ligand: A Biophysical Approach

Quadruplex (G(4)) forming sequences in telomeric DNA and c-myc promoter regions of human DNA are associated with tumorogenesis. Ligands that can facilitate or stabilize the formation and increase the stabilization of G(4) can prevent tumor cell proliferation and have been regarded as potential anti-...

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Detalles Bibliográficos
Autores principales: Sengupta, Bidisha, Pahari, Biswapathik, Blackmon, Laura, Sengupta, Pradeep K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681855/
https://www.ncbi.nlm.nih.gov/pubmed/23785423
http://dx.doi.org/10.1371/journal.pone.0065383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681855/
https://www.ncbi.nlm.nih.gov/pubmed/23785423
http://dx.doi.org/10.1371/journal.pone.0065383

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