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Targeted delivery of tumor necrosis factor-related apoptosis-inducing ligand to keratinocytes with a pemphigus monoclonal antibody

We determined the feasibility of using an anti-desmoglein (Dsg) monoclonal antibody, Px44, to deliver a biologically active protein to keratinocytes. Recombinantly produced Px44-green fluorescent protein (GFP) injected into mice and skin organ culture delivered GFP to the cell surface of keratinocyt...

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Detalles Bibliográficos
Autores principales: Kouno, Michiyoshi, Lin, Chenyan, Schechter, Norman, Siegel, Don, Yang, Xiaoping, Seykora, John T., Stanley, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681880/
https://www.ncbi.nlm.nih.gov/pubmed/23439393
http://dx.doi.org/10.1038/jid.2013.85