Pharmacokinetics Study of Recombinant Hirudin in the Plasma of Rats Using Chromogenic Substrate, ELISA, and Radioisotope Assays

AIM: To compare the analytical methods used to study the pharmacokinetics of recombinant hirudin in the plasma of rats that had been injected with (125)I-recombinant hirudin. METHODS: 2.0 mg/kg (125)I-recombinant hirudin were injected intravenously into rats. The recombinant hirudins in the plasma w...

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Detalles Bibliográficos
Autores principales: Jiang, Su-yun, Jiao, Jian, Zhang, Ting-ting, Xu, Yong-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681893/
https://www.ncbi.nlm.nih.gov/pubmed/23785400
http://dx.doi.org/10.1371/journal.pone.0064336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681893/
https://www.ncbi.nlm.nih.gov/pubmed/23785400
http://dx.doi.org/10.1371/journal.pone.0064336

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