Fitness Costs of Mutations at the HIV-1 Capsid Hexamerization Interface

The recently available x-ray crystal structure of HIV-1 capsid hexamers has provided insight into the molecular interactions crucial for the virus’s mature capsid formation. Amino acid changes at these interaction points are likely to have a strong impact on capsid functionality and, hence, viral in...

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Detalles Bibliográficos
Autores principales: Manocheewa, Siriphan, Swain, J. Victor, Lanxon-Cookson, Erinn, Rolland, Morgane, Mullins, James I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681919/
https://www.ncbi.nlm.nih.gov/pubmed/23785468
http://dx.doi.org/10.1371/journal.pone.0066065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681919/
https://www.ncbi.nlm.nih.gov/pubmed/23785468
http://dx.doi.org/10.1371/journal.pone.0066065

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