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Fitness Costs of Mutations at the HIV-1 Capsid Hexamerization Interface
The recently available x-ray crystal structure of HIV-1 capsid hexamers has provided insight into the molecular interactions crucial for the virus’s mature capsid formation. Amino acid changes at these interaction points are likely to have a strong impact on capsid functionality and, hence, viral in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681919/ https://www.ncbi.nlm.nih.gov/pubmed/23785468 http://dx.doi.org/10.1371/journal.pone.0066065 |