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IL1RAPL1 Associated with Mental Retardation and Autism Regulates the Formation and Stabilization of Glutamatergic Synapses of Cortical Neurons through RhoA Signaling Pathway

Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is associated with X-linked mental retardation and autism spectrum disorder. We found that IL1RAPL1 regulates synapse formation of cortical neurons. To investigate how IL1RAPL1 controls synapse formation, we here screened IL1RAPL1-interactin...

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Detalles Bibliográficos
Autores principales: Hayashi, Takashi, Yoshida, Tomoyuki, Ra, Moonjin, Taguchi, Ryo, Mishina, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681934/
https://www.ncbi.nlm.nih.gov/pubmed/23785489
http://dx.doi.org/10.1371/journal.pone.0066254