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Distinct Roles for CBP and p300 on the RA-Mediated Expression of the Meiosis Commitment Gene Stra8 in Mouse Embryonic Stem Cells

In mammalian germ cells, meiotic commitment requires the expression of Stimulated by retinoic acid gene 8 (Stra8), which is transcriptionally activated by retinoic acid (RA). However, little is known about the epigenetic mechanism by which RA induces Stra8 expression. Utilizing a chromatin immunopre...

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Detalles Bibliográficos
Autores principales: Chen, Wen, Jia, Wenwen, Wang, Kai, Si, Xiaoxing, Zhu, Songcheng, Duan, Tao, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681938/
https://www.ncbi.nlm.nih.gov/pubmed/23785470
http://dx.doi.org/10.1371/journal.pone.0066076